iS Clinical Super Serum Advance+ | 15% Vitamin C Brightening & Firming Serum

Fifteen percent Vitamin C with Copper Tripeptide-1 and Centella Asiatica in a single daily serum. Super Serum Advance+ is iS Clinical's most comprehensive antioxidant and brightening treatment, combining the highest Vitamin C concentration in the range with a growth factor peptide that is clinically proven to stimulate collagen synthesis and one of the most effective botanical healing actives in skincare.

The result is a serum that protects against future photodamage, reverses existing sun damage, firms and brightens simultaneously, and does something that most Vitamin C serums cannot: visibly improves the appearance of hypertrophic scar tissue and fine stretch marks.

Who is Super Serum Advance+ best for?

• Significant photodamage, sun spots and uneven skin tone requiring high-strength Vitamin C correction
• Loss of firmness and collagen decline needing peptide support alongside antioxidant treatment
• Hypertrophic or raised scarring wanting non-invasive topical improvement
• Those on GLP-1 medications experiencing accelerated skin ageing and volume loss
• Post-procedure maintenance where collagen stimulation and antioxidant protection are needed simultaneously
• Those wanting a single morning serum that covers antioxidant protection, brightening and firming

Key ingredients and why they matter

• ADVANCE+ Vitamin C 15% (stabilised L-Ascorbic Acid): iS Clinical's proprietary stabilised Vitamin C at a high concentration for maximum antioxidant protection, melanin inhibition and collagen synthesis support. Stabilised for consistent potency throughout the product's lifecycle
• Copper Tripeptide-1: A growth factor analogue that is clinically proven to stimulate collagen synthesis in dermal fibroblasts, increase total proteins and glycosaminoglycans in the dermis and visibly reduce fine lines and wrinkles with continued use. The peptide responsible for the serum's visible firming results over time
• Centella Asiatica (Asiaticoside, Asiatic Acid, Madecassic Acid): One of the most extensively studied wound-healing botanicals in dermatology. Promotes collagen synthesis, reduces scar tissue, calms inflammation and supports barrier repair. The active behind the serum's documented improvement in hypertrophic scarring

What results can you expect?

Brighter, more even and more protected skin within 2 to 4 weeks. Visible improvements in fine lines, firming and overall skin quality develop over 8 to 12 weeks of consistent daily use. Hypertrophic scar appearance improves progressively over 3 to 6 months.

How we use Super Serum Advance+ at Face for Soul

As a pharmacist prescriber specialising in skin health, Super Serum Advance+ is the iS Clinical morning serum I most consistently recommend for patients with significant photodamage and those wanting meaningful collagen support from their daily antioxidant step. The Copper Tripeptide-1 elevates it significantly above standard Vitamin C serums and the clinical evidence behind it is genuinely robust.

I also recommend it regularly to patients preparing for or recovering from laser, IPL and microneedling treatments, where daily antioxidant protection and collagen support before and after procedures materially improve outcomes. For patients on GLP-1 medications, the combination of Vitamin C, Copper Tripeptide-1 and Centella Asiatica addresses the accelerated collagen decline and skin laxity that many patients experience alongside weight loss.

Complete your iS Clinical morning routine

Apply Super Serum Advance+ to clean skin after the iS Clinical Cleansing Complex, then follow with iS Clinical Moisturizing Complex or Daily Dynamic Hydrator, and finish with iS Clinical Extreme Protect SPF 40 or Eclipse SPF 50+. In the evening, the iS Clinical Active Serum or Youth Serum with Copper Tripeptide-1 continues the correction and renewal while you sleep.

Frequently Asked Questions

How does it compare to a standard Vitamin C serum?
Most Vitamin C serums simply provide antioxidant protection and mild brightening. Super Serum Advance+ adds Copper Tripeptide-1 for clinically proven collagen stimulation and Centella Asiatica for scar reduction and healing support. It does considerably more than a standard antioxidant serum at the same price range.

Is it suitable for scarring?
Yes. The Centella Asiatica complex has documented efficacy in reducing the appearance of hypertrophic (raised) scar tissue and fine stretch marks. Results are progressive over 3 to 6 months of consistent use.

Is it suitable if I am on GLP-1 medication?
Yes. The triple action of antioxidant protection, collagen stimulation from Copper Tripeptide-1 and healing support from Centella Asiatica addresses several dimensions of the accelerated skin ageing that GLP-1 patients experience.

Is iS Clinical cruelty-free?
Yes. iS Clinical does not test on animals.

Is it vegan?
iS Clinical formulates without animal-derived ingredients in the majority of its products. Please contact us if you have specific ingredient concerns.

How to Use

Apply to clean skin morning and evening before moisturiser. Follow with SPF in the morning.