Revision Skincare D·E·J Face Cream | Comprehensive Age-Defying Moisturiser

Most moisturisers work on the surface of the skin. D·E·J Face Cream works where ageing actually begins.

The Dermal-Epidermal Junction (DEJ) is the basement membrane where the dermis and epidermis meet. During youth it is deep and wavy, supporting firm, dense and resilient skin. With age, it flattens, the proteins that hold it together break down and the skin above begins to sag, thin and lose its structure. No amount of surface moisturising can reverse this. D·E·J Face Cream was formulated specifically to strengthen this layer, using a clinically proven combination of peptides and bioactive ingredients to stimulate the production of multiple DEJ proteins including Collagen IV, Collagen VII, Laminin-5, Fibronectin and Elastin, restoring the biological foundation that keeps skin looking firm and youthful.

In a 12-week clinical study, D·E·J Face Cream used twice daily delivered visible improvements in radiance, fine lines, forehead lines and overall skin smoothness.

Who is D·E·J Face Cream best for?

• Mature or menopausal skin experiencing loss of firmness, density and structural support
• Those wanting an all-in-one advanced moisturiser that addresses the root causes of ageing rather than the surface signs
• Those on GLP-1 medications experiencing accelerated facial ageing and volume loss
• Anyone wanting to complement or extend the results of aesthetic treatments
• Those who have been disappointed by standard anti-ageing moisturisers and want clinical-level results

Key ingredients and why they matter

• Acetyl Tetrapeptide-2 and Palmitoyl Hexapeptide-14: Clinically proven to increase the synthesis of Collagen IV, Fibronectin and Elastin in the DEJ, directly addressing the flattening and protein loss that causes visible skin ageing
• Rhamnose and Silanetriol: Stimulate the production of multiple DEJ proteins including Collagen IV, Collagen VII and Laminin-5, restoring the DEJ structure to resemble that of younger skin
• THD Ascorbate (stable Vitamin C): Enhances the DEJ to promote firmness and brightens skin, backed by peer-reviewed published clinical studies
• Lipid Technology (Ceramides, Cholesterol, Fatty Acids): Biomimics the skin's natural lipid composition to restore and protect the moisture barrier
• Prebiotic (Alpha-Glucan Oligosaccharide) and Postbiotic (Pseudoalteromonas Ferment Extract): Support the skin's microbiome diversity and balance for healthier, more resilient skin over time
• Squalane, Hyaluronic Acid and Vitamin E: Provide comprehensive hydration, nourishment and antioxidant protection

Clinical results after 12 weeks of twice-daily use

• Visible improvement in radiance and skin brightness
• Reduction in fine lines and forehead lines
• Improvement in overall skin smoothness and texture
• Strengthened DEJ structure supporting long-term firmness and density

How we use D·E·J Face Cream at Face for Soul

As a pharmacist prescriber specialising in skin health, D·E·J Face Cream is one of the most scientifically compelling moisturisers I recommend. The concept of formulating specifically for the DEJ rather than the skin's surface is genuinely novel, and the clinical data supporting the DEJ protein stimulation is published and peer-reviewed. For patients who want their daily moisturiser to be doing something meaningful rather than just providing surface hydration, this is the most credible option in its category.

It is particularly relevant for patients on GLP-1 medications, where the combination of volume loss and skin laxity benefits from structural support at the DEJ level, and for patients undergoing collagen-stimulating aesthetic treatments who want to maintain and extend results with their daily skincare.

Complete your D·E·J routine

D·E·J Face Cream is the moisturising step in the Revision D·E·J protocol. Pair it with the Revision D·E·J Daily Boosting Serum as your treatment serum for maximum DEJ stimulation, the Revision D·E·J Eye Cream for the eye area and the Revision D·E·J Night Face Cream in the evening. For daily sun protection, the Revision Intellishade TruPhysical SPF 45 applies as the final morning step.

Frequently Asked Questions

What is the DEJ and why does it matter?
The Dermal-Epidermal Junction is the basement membrane where the skin's outer and inner layers meet. It is the structural foundation that supports skin firmness, density and youthfulness. As we age, the DEJ flattens and the proteins that hold it together decline. Addressing this layer is what makes Revision D·E·J products clinically distinct from standard anti-ageing moisturisers.

Is it suitable if I am on GLP-1 medication?
Yes. Patients on GLP-1 medications such as Ozempic, Wegovy, Mounjaro or Zepbound commonly experience skin laxity and volume loss. D·E·J Face Cream addresses the structural causes of these changes by stimulating DEJ protein production, making it one of the most clinically targeted moisturisers for this patient group.

Which treatments does it pair well with?
D·E·J Face Cream pairs well with microneedling, radiofrequency, laser, chemical peels and injectable treatments. Using it consistently around procedure appointments supports the DEJ and helps maintain and extend clinical results. Always follow your clinician's post-treatment advice.

Is it suitable for sensitive skin?
Yes. All Revision Skincare products are formulated to skin-neutral pH and without denatured alcohol. The prebiotic and postbiotic complex supports the skin microbiome, making it well tolerated by most skin types including sensitive skin.

Is Revision Skincare cruelty-free?
Yes. Revision Skincare does not test on animals.

Is it vegan?
Revision Skincare formulates without animal-derived ingredients in the majority of its products. Please contact us if you have specific ingredient concerns.

How to Use

Apply to clean skin on the face and neck morning and evening. Follow with Revision Intellishade TruPhysical SPF 45 in the morning.