skinbetter science® Alto Advanced Defense and Repair Serum™

Alto Defense Serum brought 19 antioxidants together. Alto Advanced Defense and Repair Serum takes the next step: comprehensive antioxidant protection plus active repair, in a single morning serum.

Where Alto Defense focuses on defending against environmental damage, Alto Advanced goes further by actively repairing DNA-level cellular damage that has already occurred, using a carefully engineered combination of Vitamins C and E, Ferulic Acid, Niacinamide and a targeted repair complex that works at the level where environmental damage begins. For those wanting the most comprehensive morning serum skinbetter science offers, this is it.

Who is Alto Advanced Defense and Repair Serum best for?

• Those wanting both antioxidant protection and active cellular repair in a single morning step
• More significant photodamage, uneven tone and visible environmental skin ageing
• Those on GLP-1 medications wanting maximum skin protection and repair during weight loss
• Those wanting to step up from Alto Defense Serum for more intensive correction
• Anyone wanting the most comprehensive morning antioxidant and repair serum available

Key ingredients and why they matter

• Vitamins C, E and Ferulic Acid: The clinically gold-standard antioxidant combination that works synergistically to provide significantly enhanced protection against UV-induced free radical damage compared to any single antioxidant alone
• Niacinamide: Reduces the appearance of redness and uneven tone while supporting the skin barrier and improving overall skin quality
• DNA Repair Complex: Targets cellular damage at the level where environmental ageing begins, going beyond surface protection to actively address what has already occurred
• Brightening and Calming Botanical Blend: Supports an even, luminous complexion while maintaining skin comfort throughout daily use

What results can you expect?

Visible improvements in skin tone, radiance and texture alongside the protective benefits of daily antioxidant use. Most users notice progressively brighter, more even and more resilient skin over 8 to 12 weeks of consistent morning use. The active repair component addresses cumulative damage that antioxidant-only serums cannot reverse.

How we use Alto Advanced at Face for Soul

As a pharmacist prescriber, Alto Advanced is the morning serum I recommend for patients who have significant photodamage and want more than protection alone from their antioxidant step. It works particularly well as the morning counterpart to Intensive AlphaRet Overnight Cream for patients requiring the most comprehensive skinbetter science protocol available.

Complete your intensive skinbetter science routine

Alto Advanced pairs naturally with the skinbetter science Intensive AlphaRet Overnight Cream for a complete day and night intensive correction protocol. Add the skinbetter science Even Tone Correcting Serum in the evening for tone correction alongside overnight renewal, the skinbetter science InterFuse Treatment Cream FACE and NECK for firming, and the skinbetter science EyeMax AlphaRet Overnight Cream for the eye area.

Frequently Asked Questions

What is the difference between Alto Defense and Alto Advanced?
Alto Defense uses WEL Technology to deploy 19 antioxidants for comprehensive environmental defence. Alto Advanced adds an active DNA repair complex and the clinically proven Vitamins C, E and Ferulic Acid combination for active repair of existing damage alongside protection against future damage. Alto Advanced is the more intensive of the two.

Is skinbetter science cruelty-free?
Yes. skinbetter science does not test on animals.

Is it vegan?
Yes. Alto Advanced Defense and Repair Serum is formulated without animal-derived ingredients.

How to Use

Apply a thin layer to clean, dry skin on the face, neck and décolleté each morning before moisturiser and SPF.